CASR Rabbit pAb (APR20807N)
产品名称: CASR Rabbit pAb (APR20807N)
英文名称: CASR Rabbit pAb (APR20807N)
产品编号: APR20807N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围: WB (Rat pulmonary arterial smooth muscle) IHC (Rattus norvegicus)
安诺伦(北京)生物科技有限公司
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分子量:Calculated MW: 120kDa/121kDa Observed MW: 130-260KDa 细胞定位:Cell membrane, Multi-pass membrane protein 稀释方法:WB 1:500 - 1:2000 IHC 1:50 - 1:200 总结:The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.