产品概述：Purified recombinant protein of Human ADAM metallopeptidase with thrombospondin type 1 motif, 8 (ADAMTS8), with C-terminal His tag, secretory expressed in HEK293 cells, 50ug

蛋白长度：A DNA sequence from GoldORF clone, [GH42179V], encoding the region Ala27-Leu889 of ADAMTS8

表达系统：HEK293

种属：Human

标签类型：C-His

分子量：95 kDa

通用名：ADAMTS8

总结：This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. Reduced expression of this gene has been observed in multiple human cancers and this gene has been proposed as a potential tumor suppressor. [provided by RefSeq, Feb 2016]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：PBS, pH7.4, 10% glycerol;

别名：ADAM-TS8; METH2