分子量：Calculated MW: 167kDa/172kDa
Observed MW: 168kDa

细胞定位：Cytoplasm, Membrane

稀释方法：WB 1:500 - 1:2000
IHC 1:50 - 1:100

总结：Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.