TLR4 Rabbit pAb (APR18382N)-抗体-抗体-生物在线
安诺伦(北京)生物科技有限公司
TLR4 Rabbit pAb (APR18382N)

TLR4 Rabbit pAb (APR18382N)

商家询价

产品名称: TLR4 Rabbit pAb (APR18382N)

英文名称: TLR4 Rabbit pAb (APR18382N)

产品编号: APR18382N

产品价格: null

产品产地: 美国

品牌商标: Leading Biology

更新时间: null

使用范围: WB (Mus musculus, Rattus norvegicus, Homo sapiens)

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分子量:Calculated MW: 73kDa/91kDa/95kDa
Observed MW: 96KDa

细胞定位:Cell membrane, Single-pass type I membrane protein

稀释方法:WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

总结:The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.